Seizures-
Child: Loading dose: 15-20 mg/kg IV at 1-3 mg/kg/min, or 5 mg/kg PO or 250 mg/m2 PO qd divided q 8-12 h; maintenance: 4-8 mg/kg PO, IV qd divided q 12 h. Max 300 mg qd.
Adult: Loading dose:10-15 mg/kg slow IV, max 50 mg/min; PO loading dose: 1 gram in 3 divided doses (400,300,300 mg) q 2 h. Maintenance: 300 mg PO qd (ext only); initially divided dose tid (ext or prompt).
Neuritis pain-
Adult: 200-600 mg PO qd in divided doses.
Skeletal muscle relaxant-
Adult: 200-600 mg PO qd prn.
Seizure prophylaxis during neurosurg-
Adult: 100-200 mg IV q 4 h perioperative, postoperative. |