| Drug induced Cardiomyopathy, Arrhythmias, CHF, Pre-existing heart disease. Extravasation of Idarubicin can cause severe local tissue necrosis, Hepatic & Renal function impairment, Hyperuricemia secondary to rapid lysis of leukaemic cells, Myelosuppression, Bleeding, Infectious disease, Prior Anthracycline Chemotherapy. |