Serious infection
Neonate 0-4 wk and < 1,200g: 7.5 mg/kg IM, IV q 18 h.
Neonate < 1 wk and < 1,200-2,000 gram:7.5 mg/kg IM, IV q 12 h.
Neonate < 1 wk and > 2,000 gram: 7.5-10 mg/kg IM, IV q 12 h.
Neonate > 1 wk and < 1,200-2,000 gram: 7.5-10 mg/kg IM, IV q 8-12 h.
Neonate > 1 wk and > 2,000 gram: 10 mg/kg IM, IV q 8 h.
Infant, child, adult: 15 mg/kg/day divided q 8-12 h IM, IV in 100-200 ml D5W over 30-60 min. Max 1.5 gram/day.
Adult: 4-20 mg intrathecally or intraventricularly × 1 with IM or IV administration. |