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Interactions: | AmoxycillinAdverse Effect: loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
Amoxycillin + Bromhexine Comb.Adverse Effect: Loss of aminoglycoside efficacyClinical Management: Monitor patients for aminoglycoside effectiveness.
Amoxycillin + Carbocisteine Comb.Adverse Effect: Loss of aminoglycoside efficacyClinical Management: Monitor patients for aminoglycoside effectiveness.
Amoxycillin + Clavulanic Acid Comb.Adverse Effect: Loss of aminoglycoside efficacyClinical Management: Monitor patients for aminoglycoside effectiveness.
Amoxycillin + Cloxacillin Comb.Adverse Effect: Loss of aminoglycoside efficacyClinical Management: Monitor patients for aminoglycoside effectiveness.
AmpicillinAdverse Effect: loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
AtracuriumAdverse Effect: enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysisClinical Management: Avoid concomitant use of Gentamicin and Atracurium if possible. Concurrent use of Gentamicin and Atracurium requires close monitoring of the patients clinical condition, especially respiratory and oxygenation status.
BacampicillinAdverse Effect: Loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
Benzathine PenicillinAdverse Effect: Loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
Benzyl PenicillinAdverse Effect: loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
BumetanideAdverse Effect: ototoxicityClinical Management: Consider periodic auditory testing for patients with renal dysfunction, or for patients on high doses of either drug.
CapreomycinAdverse Effect: gentamicin toxicity (ototoxicity, nephrotoxicity)Clinical Management: If concomitant administration is necessary, respiratory function, renal function and auditory function should be monitored closely.
CarbenicillinAdverse Effect: Loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
CarboplatinAdverse Effect: ototoxicityClinical Management: If clinically acceptable, an alternate antibiotic (a non-aminoglycoside) may be preferred.
CefaclorAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cefaclor could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CefadroxilAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cefadroxil could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CefazolinAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cefazolin could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CefiximeAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cefixime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CefoperazoneAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cefoperazone could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CefotaximeAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cefotaxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CefpiromeAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cefpirome could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CefpodoximeAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cefpodoxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CeftazidimeAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Ceftazidime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CeftizoximeAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Ceftizoxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CeftriaxoneAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Ceftriaxone could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CefuroximeAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cefuroxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CephalexinAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cephalexin could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CephaloridineAdverse Effect: an increased risk of nephrotoxicityClinical Management: Coadministration of Gentamicin with Cephaloridine could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
CloxacillinAdverse Effect: Loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
CyclosporinAdverse Effect: NephrotoxicityClinical Management: Monitor for signs and symptoms of nephrotoxicity and administer the drug with caution.
FrusemideAdverse Effect: ototoxicity and/or nephrotoxicityClinical Management: Consider periodic auditory testing for patients on high doses of either drug. Also monitor renal function.
IndomethacinAdverse Effect: Gentamicin toxicity (renal dysfunction, ototoxicity)Clinical Management: Monitor aminoglycoside levels closely for one to two days as well as renal function after starting or discontinuing indomethacin.
Mg. saltsAdverse Effect: Neuromuscular weaknessClinical Management: Monitor patients for respiratory dysfunction and apnea. If neuromuscular blockade occurs, discontinue Gentamicin and change antibiotic therapy. Patients receiving large cumulative dose of Gentamicin should have serum calcium, magnesium, potassium, and creatinine monitored.
PancuroniumAdverse Effect: enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysisClinical Management: Avoid concomitant use of Gentamicin and Pancuronium if possible. Concurrent use of Gentamicin and Pancuronium requires close monitoring of the patients clinical condition, especially respiratory and oxygenation status.
Penicillin V ( Phenoxymethyl )Adverse Effect: loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
PipecuroniumAdverse Effect: enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysisClinical Management: Avoid concomitant use of Gentamicin and Pipecuronium if possible. Concurrent use of Gentamicin and Pipecuronium requires close monitoring of the patients clinical condition, especially respiratory and oxygenation status.
PiperacillinAdverse Effect: Loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
Procaine PenicillinAdverse Effect: Loss of Gentamicin efficacyClinical Management: Monitor patients for Gentamicin effectiveness.
Succinyl CholineAdverse Effect: enhanced neuromuscular blockadeClinical Management: Titrate the dose of Succinyl Choline carefully. Monitor patients not on a ventilator for respiratory paralysis.
VancomycinAdverse Effect: nephrotoxicityClinical Management: Renal function tests should be closely monitored.
VecuroniumAdverse Effect: enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysisClinical Management: Avoid concomitant use of Gentamicin and Vecuronium if possible. Concurrent use of Gentamicin and Vecuronium requires close monitoring of the patients clinical condition, especially respiratory and oxygenation status. |
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