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| Dosages: | Serious infection
Neonate < 1 wk: 2.5 mg/kg IM or IV infusion q 12 h over 30 min-2 h.
Neonate > 1 wk, infant: 2.5 mg/kg IM or IV infusion q 8-12 h.
Child: 2-2.5 mg/kg IM or IV infusion q 8 h.
Adult: 3 mg/kg/day IM or IV infusion over 30 min-2 h in divided doses q 8 h. Give IV push prn. For life-threatening infection, up to 5 mg/kg/day in 3-4 divided doses.
Meningitis
Child: Systemic treatment as above. Or 1-2 mg intrathecally qd.
Adult: Systemic treatment as above. Or 4-8 mg intrathecally qd.
Endocarditis prophylaxis for GI, GU procedure, surgery
Child: 2 mg/kg IM or IV 30-60 min before procedure and q 8 h after × 2 doses. Give with aqueous penicillin G or ampicillin.
Adult: 1.5 mg/kg IM or IV 30-60 min before procedure and q 8 h after × 2 doses. Give with aqueous penicillin G or ampicillin.
PID
Adult: 2 mg/kg IM or IV; then 1.5 mg/kg q 8 h.
External ocular infection
Child, adult: 1-2 drops in eye q 4 h. In severe infection, up to 2 drops q h. Apply oint to lower conjunctival sac bid or tid.
Infection; superficial burns; skin ulcers; infected lacerations, abrasions, insect bites, minor surgery wounds
Child > 1 yr, adult: Rub in small amount gently tid-qid, with or without gauze dressing. |
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