UTI, shigellosis
Infant, child > 2 month: 8 mg/kg trimethoprim and 40 mg/kg sulfamethoxazole PO qd in 2 divided doses q 12 h (10 day for UTI; 5 day for shigellosis).
Adult: 1 double-strength or 2 regular-strength tab PO q 12 h × 10-14 day or 5 day for shigellosis. Or 8-10 mg/kg (based on trimethoprim) IV qd in 2-4 divided doses for up to 14 day (5 day for shigellosis). Max 960 mg qd.
OM
Infant, child > 2 month: 8 mg/kg trimethoprim and 40 mg/kg sulfamethoxazole PO qd in 2 divided doses q 12 h × 10 day.
Pneumocystis carinii pneumonitis
Infant, child > 2 month, adult: 15-20 mg/kg trimethoprim and 75-100 mg/kg sulfamethoxazole PO qd in divided doses q 6-8 h × 14-21d.
Travelers diarrhea
Adult: 1 double-strength or 2 regular-strength tab q 12 h × 5 day.
Pertussis
Child: 40 mg/kg/day PO in 2 divided doses.
Adult: 320 mg PO qd in 2 divided doses.
Cholera
Child: 5 mg/kg PO bid × 3 day.
Adult: 160 mg PO bid × 3 day. |