Cimetidine
Adverse Effect: an increased risk of tretinoin toxicity Clinical Management: Monitor patients for signs and symptoms of tretinoin toxicity (headache, fever, weakness, and fatigue).
Diltiazem
Adverse Effect: an increased risk of tretinoin toxicity Clinical Management: Monitor patients for signs and symptoms of tretinoin toxicity (headache, fever, weakness, and fatigue
Erythromycin
Adverse Effect: an increased risk of tretinoin toxicity Clinical Management: Monitor patients for signs and symptoms of tretinoin toxicity (headache, fever, weakness, and fatigue).
Ketoconazole
Adverse Effect: an increased risk of tretinoin toxicity Clinical Management: Monitor patients for signs and symptoms of tretinoin toxicity (headache, fever, weakness, and fatigue).
Phenobarbitone
Adverse Effect: decreased efficacy of tretinoin Clinical Management: Monitor patients for signs of tretinoin efficacy. The withdrawal of phenobarbital therapy may be warranted in some cases.
Rifampicin
Adverse Effect: decreased efficacy of tretinoin Clinical Management: Monitor patients for signs of tretinoin efficacy. The withdrawal of rifampin therapy may be warranted in some cases.
Verapamil
Adverse Effect: an increased risk of tretinoin toxicity Clinical Management: Monitor patients for signs and symptoms of tretinoin toxicity (headache, fever, weakness, and fatigue) |