Neutrophil count of > 1500 cells/mm3, platelet count of > 100,000 cells/mm3 is required before first dose administration.
IV: 1.5mg/m2 administered over a period of 30mts for 5 consecutive days, starting on day 1 of 21-day course, 4 courses if tumor progression is not there.
In severe neutropenia/platelet count < 25,000cells/mm3, reduce dose by 0.25mg/m2 for subsequent courses |