Bupivacaine
Adverse Effect: an increased hypnotic effect of propofol Clinical Management: In patients receiving bupivacaine in soft tissue before induction of anesthesia with propofol, downward dosage adjustments in propofol are necessary.
Diazepam
Adverse Effect: Diazepam toxicity (CNS depression) Clinical Management: Monitor for excessive sedation and provide medical support if required.
Halothane
Adverse Effect: Propofol toxicity (respiratory depression) Clinical Management: Monitor respiratory depression.
Lignocaine
Adverse Effect: an increased hypnotic effect of propofol Clinical Management: In patients receiving lidocaine in soft tissue before induction of anesthesia with propofol, downward dosage adjustments in propofol are necessary.
Succinyl Choline
Adverse Effect: bradycardia Clinical Management: If concurrent therapy is required, monitor cardiac function carefully. Pre-treatment with atropine may prevent the bradycardia response reported with concomitant administration.
Theophylline
Adverse Effect: Decreased propofol effectiveness Clinical Management: It is important to let your physician know all medications you are taking before undergoing surgery |