Cystinuria-
Child: 30 mg/kg PO qd divided qid 0.5-1 h ac and = 2 h after pm meal. Adjust dose to urinary cystine excretion < 100 mg qd with renal calculi or 100-200 mg qd without calculi.
Adult: 250 mg PO qd in 4 divided doses, then increase dose. Usual dose, 2 gram qd. Adjust dose to urinary cystine excretion < 100 mg qd with renal calculi or 100-200 mg qd without calculi.
Heavy metal poisoning-
Child: 30-40 mg/kg or 600-750 mg/m2 PO qd × 1-6 month.
Adult: 500-1,500 mg PO qd × 1-2 month.
RA, Feltys syndrome-
Adolescent, adult: 125-250 mg PO qd, increase by 5-250 mg qd q1-3 month prn. Max 1.5 gram qd. |