Molecule : Phenytoin
Adverse Effect: Loss of paclitaxel efficacy Clinical Management: In patients receiving phenytoin concurrently with paclitaxel, monitor for an adequate response to paclitaxel. Doses of paclitaxel may need to be increased.
Molecule : Vinorelbine
Adverse Effect: Incidence of neuropathy #Clinical Management: Monitor for signs and symptoms of neuropathy & avoid the concurrent use if possible. |