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| Interactions: | Molecule : Clomipramine
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia
Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Orciprenaline are substantially enhanced in the presence of Clomipramine .Concomitant use should be avoided.
Molecule : Dothiepin
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia
Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Orciprenaline are substantially enhanced in the presence of Dothiepin.Concomitant use should be avoided.
Molecule : Doxepin
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia
Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Orciprenaline are substantially enhanced in the presence of Doxepin .Concomitant use should be avoided.
Molecule : Imipramine
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia
Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Orciprenaline are substantially enhanced in the presence of Imipramine.Concomitant use should be avoided.
Molecule : Nortriptyline
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia
Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Orciprenaline are substantially enhanced in the presence of Nortriptyline .Concomitant use should be avoided. If these drugs are given together, careful monitoring and a dose reduction of the sympathomimetic is required.
Molecule : Selegiline
Adverse Effect: Increased hypertensive effects
Clinical Management: Monitor patients for clinical effects of acute blood pressure elevation (headache, arrhythmia, vomiting, fever). Should a hypertensive crisis develop, discontinue the drug and immediately begin medical therapy to lower blood pressure. Nitroprusside, nitroglycerin, phentolamine, and labetalol are among the drugs that have been successfully used.
Molecule : Theophylline
Adverse Effect: Decreased theophylline concentrations
Clinical Management: Theophylline serum concentrations should be closely monitored when isoproterenol is added, discontinued, or when dosing changes occur. Dosing adjustments of theophylline may be necessary.
Molecule : Trimipramine
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia
Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Orciprenaline are substantially enhanced in the presence of Trimipramine.Concomitant use should be avoided. |
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