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| Interactions: | Antacids Comb.Adverse Effect reduced lansoprazole bioavailabilityClinical Management Administer lansoprazole at least one hour after antacid therapy
ClarithromycinAdverse Effect Glossitis, stomatitis, or black tongueClinical Management When lansoprazole is used with clarithromycin monitor patients for changes in the oral mucosa. Discontinue the clarithromycin and reduce the dose of lansoprazole if needed.
Itraconazole Adverse Effect loss of itraconazole efficacyClinical Management Itraconazole should be administered with a cola beverage in patients receiving Lansoprazole.
Ketoconazole Adverse Effect loss of ketoconazole efficacyClinical Management Concurrent administration of ketoconazole and Lansoprazole should be undertaken with caution. If concurrent use cannot be avoided, aggressively monitor these patients for continued antifungal efficacy.
SucralfateAdverse Effect Reduced lansoprazole bioavailabilityClinical Management Lansoprazole should be administered at least 30 minutes prior to sucralfate therapy.
TheophyllineAdverse Effect Slightly decreased theophylline serum concentrationsClinical Management It would be prudent to monitor theophylline serum concentrations when starting or stopping lansoprazole. |
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