UTI, systemic infection- Infant > 2 month, child: 75 mg/kg (or 2 gram/m2) PO in 1 dose then 150 mg/kg (or 4 gram/m2) PO qd in divided doses 4-6 h. Max 6 gram/day. Adult: 2-4 gram PO; then 4-8 gram PO qd in divided doses q 4-6 h. Max 6 gram/24 h. If CrCl is 10-50 ml/min, give recommended dose every 8-12 h. If < 10 ml/min, give recommended dose every 24 h.
Conjunctivitis, corneal ulcer, superficial ocular infection; adjunct in trachoma- Adolescent, adult: 1-2 drops in lower conjunctival sac q 1-4 h. If CrCl is 10-50 ml/min, give recommended dose every 8-12 h. If < 10 ml/min, give recommended dose every 24 h. |