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| Dosages: | Oral: DUODENAL & BENIGN GASTRIC ULCER: 300mg OD at bedtime OR 150mg bid. After 4-8 weeks 150mg at bedtime.
REFLUX OESOPHAGITIS: 150mg bid upto 8 weeks.
ZES: 150mg bid/tid. Max. upto 6g/day.
Px. of STRESS ULCERS: 150mg bid.
PREVENTION OF ACID ASPIRATION: 150mg, 2 hours before induction. may be repeated every 6 hours as required.
PREVENTION OF MENDELSONS SYNDROME: 150mg 2-4 hours before surgery. ; Obstetrics Patients: 150mg every 6 hours until delivery.
IV/IM: PATHOLOGICAL HYPERSECRETORY CONDITIONS: 50-100mg every 6 hours.
PREVENTION OF MENDELSONS SYNDROME: 50-100mg.
RENAL IMPAIRMENT: If the Creatinine Clearance is < 50ml/min the dose is reduced to 150mg every 24 hours.
Duodenal, gastric ulcer; hypersecretory conditions; such as Zollinger-Ellison syndrome-
Child (duodenal, gastric ulcer treatment): 2-4 mg/kg PO bid or 2-4 mg/kg IV qd dil given over 15-20 min. Max 300 mg/day.
Adolescent, adult: 150 mg PO bid or 300 mg hs. Up to 6 gram/day in pt with Zollinger-Ellison syndrome. Or 50 mg IV, IM q 6-8 h.
Maintenance treatment in duodenal ulcer-
Adolescent, adult: 150 mg PO hs.
Prophylaxis of stress ulcer-
Adolescent, adult: 150 mg IV infusion in 250 ml compatible solution at 6.25 mg/h with pump.
GERD-
Child: 2-8 mg/kg IV, PO tid.
Adolescent, adult: 150 mg PO bid.
Heartburn, indigestion, sour stomach-
Adolescent = 12 yr, adult: 75 mg (OTC) once qd or bid. Max 150 mg in 24 h. |
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