Carbamazepine Adverse Effect Increased risk of carbamazepine toxicity (ataxia, nystagmus, diplopia, headache, vomiting, apnea, seizures, coma) Clinical Management: For patients receiving concurrent carbamazepine and loxapine therapy, monitor for signs of carbamazepine toxicity and adjust doses accordingly.
Lithium Adverse Effect Weakness, dyskinesias, increased extrapyramidal symptoms, encephalopathy, and brain damage Clinical Management: Monitor patients closely for any signs of toxicity or extrapyramidal symptoms, especially if high doses of Loxapine and lithium are used.
Tramadol Adverse Effect Increased risk of seizures Clinical Management: Caution should be used if tramadol is to be administered to patients receiving neuroleptic therapy. If possible, avoid this combination |