Contraindicated in children with hypersensitivity to drug and in those with bone marrow suppres-sion (WBC counts of 5,OOO/mm3 or less or platelet counts of 100,OOO/mm3 or less) or potentially se-rious infections; in children who are in a poor nu-tritional state; and in those who have had major surgery within the previous month.
Also use with caution in children with widespread neoplastic infiltration of bone marrow or impaired renal or hepatic function. |