Prophylaxis of organ rejection in kidney, liver, heart, bone marrow, pancreas, cornea transplant
Child, adult: 15 mg/kg PO qd 4-12 h before transplant. Continue qd dose postoperative × 1-2 wk. Then reduce dose by 5% wkly to maintenance of 5-10 mg/kg/day. Or IV concentrated of 5-6 mg/kg 4-12 h before transplant. Postoperative, 5-6 mg/kg qd as IV dilute solution infusion (50 mg/20-100 ml over 2-6 h) until pt can tol PO. |