Antacid supplements containing alu-minum, calcium, and magnesium: May interfere with ciprofloxacin absorption. Give 2 hours before or 6 hours after ciprofloxacin.
Aminoglycosides, beta-lactams: Synergistic ef-fects have occurred with concurrent use. Use to-gether cautiously.
Iron, minerals, and vitamins: May interfere with ab-sorption of ciprofloxacin. Administer separately.
Probenecid: Interferes with renal tubular secre-tion, causing higher plasma levels of ciprofloxacin. Use together cautiously.
Sucralfate: Reduces absorption of ciprofloxacin by 50%. Monitor patient closely.
rheophylline. May increase risk of theophylline toxicity. Monitor theophylline levels.
Warfarin: Increased PT. Monitor PT.
Sun exposure: Photosensitivity reaction may oc-cur. Encourage children to take precautions. |