Lower respiratory, CNS, bone, joint, intra-abdominal, gyn, skin infection; UTI; bacteremia; septicemia; PID
Neonate = 1 wk: 50 mg/kg IV q 12 h.
Neonate 1-4 wk: 50 mg/kg IV q 8 h.
Infant, child 1 month-12 yr and < 50 kg: 50-180 mg/kg IV qd in 4-6 divided doses. Use higher doses for serious infection.
Child > 50 kg, adult: 1 gram IV or IM q 6-12 h. Up to 12 gram qd in life-threatening infection.
Gonorrhea
Adolescent, adult: 1 gram IM in 1 dose.
Perioperative prophylaxis
Adult: 1 gram IV or IM 30-90 min before surgery.
Disseminated gonococcal infection
Adolescent, adult: 1 gram IV q 8 h.
Gonococcal ophthalmia; disseminated gonococcal infection
Neonate, infant: 25-50 mg/kg IV q 8-12 h × 7 day or 50-100 mg/kg IM or IV q 12 h × 7 day. |