Cetirizine + Phenylpropanolamine + Paracetamol Comb.
Adverse Effect: hypertensive urgency or emergency Clinical Management: Avoid concurrent use. If these drugs are used together, monitor blood pressure and ask the patient about frequent headaches or palpitations as these symptoms may be prodromes of a hypertensive crisis. If a hypertensive crisis occurs discontinue the MAOI and institute therapy to lower blood pressure (5 mg of phentolamine intravenously given slowly).
Clomipramine
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Terbutaline are substantially enhanced in the presence of Clomipramine .Concomitant use should be avoided.
Dothiepin
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Terbutaline are substantially enhanced in the presence of Dothiepin.Concomitant use should be avoided.
Doxepin
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Terbutaline are substantially enhanced in the presence of Doxepin .Concomitant use should be avoided.
Imipramine
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Terbutaline are substantially enhanced in the presence of Imipramine.Concomitant use should be avoided.
Nortriptyline
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Terbutaline are substantially enhanced in the presence of Nortriptyline .Concomitant use should be avoided. If these drugs are given together, careful monitoring and a dose reduction of the sympathomimetic is required.
Selegiline
Adverse Effect: An increased risk of tachycardia, agitation, or hypomania Clinical Management: Direct-acting beta adrenergic agonist drugs should theoretically not interact with Selegiline . However, two case reports have described adverse effects, including tachycardia and hypomania, attributed to such an interaction. Close observation for such adverse effects is warranted when these agents are administered concurrently or if the beta agonist is given within two weeks of discontinuation of the MAO inhibitor.
Succinyl Choline
Adverse Effect: Enhanced neuromuscular blockade Clinical Management: Patients receiving terbutaline and succinylcholine should be monitored for prolonged neuromuscular blockade. If prolongation occurs, neostigmine (1 to 3 mg) with atropine (0.6 to 1.2 mg) may be given.
Theophylline
Adverse Effect: Decreased theophylline concentrations Clinical Management: Theophylline serum concentrations should be closely monitored when terbutaline is added, discontinued, or when dosing changes occur. Dosing adjustments of theophylline may be necessary.
Trimipramine
Adverse Effect: hypertension, cardiac arrhythmias, and tachycardia Clinical Management: The vasoconstriction and other alpha-adrenergic effects of Terbutaline are substantially enhanced in the presence of Trimipramine.Concomitant use should be avoided |