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| Interactions: | Molecule : Cisapride
Adverse Effect: Loss of cisapride efficacy
Clinical Management: The beneficial effects of cisapride are expected to be largely lost if an anticholinergic medication such as oxybutynin is given concomitantly.
Molecule : Clomipramine
Adverse Effect: Decreased clomipramine efficacy
Clinical Management: Patients receiving concurrent therapy with oxybutynin and clomipramine should be monitored for loss of clomipramine efficacy, including worsening of symptoms. Plasma levels of clomipramine may be helpful in determining if efficacy is being compromised.
Molecule : Procainamide
Adverse Effect: additive antivagal effects on A-V nodal conduction
Clinical Management: Monitor heart rate and ECG in patients given procainamide concomitantly with Oxybutynin. |
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