Seizures-
Child 4-16 yr: 8-10 mg/kg/day PO divided bid. Max 600 mg/day. Maintenance dose depends on pt wt; divided bid. If pt weighs 20-29 kg, maintenance 900 mg/. If 29.1-39 kg, maintenance 1,200 mg/day. If > 39 kg, maintenance 1,800 mg/day.
Adult: 300 mg PO bid. Increase by max 600 mg/day (300 mg PO bid) q wk. Recommended dose 1,200 mg PO divided bid.
Conversion to monotherapy for partial seizures-
Adult: 300 mg PO bid, with decrease in dose of other antiepileptics. Increase by max 600 mg/day q wk over 2-4 wk. Recommended dose 2,400 mg PO divided bid. Discontinue other antiepileptics over 3-6 wk.
Monotherapy for partial seizures-
Adult: 300 mg PO bid. Increase by 300 mg/day q 3rd day to 1,200 mg/day divided bid. |