Dosages & Reactions

Interactions:

Abciximab
Concomitant use with Indapamide and Inotropic agents is useful in cardiac failure and with hypertension increase in sensitivity of the drug
Benazepril
Adverse Effect: postural hypotension (first dose)
Clinical Management: Start with a very low dose of the Benazepril in the evening and closely monitor blood pressure for a severe hypotensive response for four hours after the initial dose. Monitor for hypotension, fluid status, and body weight regularly for up to two weeks after dose adjustments.
Captopril
Adverse Effect: postural hypotension (first dose)
Clinical Management: Start with a very low dose of the Captopril in the evening and closely monitor blood pressure for a severe hypotensive response for four hours after the initial dose. Monitor for hypotension, fluid status, and body weight regularly for up to two weeks after dose adjustments.
Celecoxib
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Enalapril
Adverse Effect: postural hypotension (first dose)
Clinical Management: Start with a very low dose of the angiotensin converting enzyme (ACE) inhibitor in the evening and closely monitor blood pressure for a severe hypotensive response for four hours after the initial dose. Monitor for hypotension, fluid status, and body weight regularly for up to two weeks after dose adjustments.
Flurbiprofen
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Ibuprofen
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Indomethacin
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Ketoprofen
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Ketorolac
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Lisinopril
Adverse Effect: postural hypotension (first dose)
Clinical Management: Start with a very low dose of the angiotensin converting enzyme (ACE) inhibitor in the evening and closely monitor blood pressure for a severe hypotensive response for four hours after the initial dose. Monitor for hypotension, fluid status, and body weight regularly for up to two weeks after dose adjustments.
Lithium
Adverse Effect: increased lithium concentrations and lithium toxicity (weakness, tremor, excessive thirst, confusion)
Clinical Management: Monitor serum lithium levels within the first five to seven days of adding or discontinuing indapamide and periodically thereafter. Lower lithium doses may be required with concomitant indapamide therapy.
Mefenamic Acid
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Meloxicam
Adverse Effect: Decreased diuretic and antihypertensive efficacy Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Nabumetone
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Naproxen
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Nimesulide
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Oxyphenbutazone
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Paracetamol
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Perindopril
Adverse Effect: postural hypotension (first dose)
Clinical Management: Start with a very low dose of the angiotensin converting enzyme (ACE) inhibitor in the evening and closely monitor blood pressure for a severe hypotensive response for four hours after the initial dose. Monitor for hypotension, fluid status, and body weight regularly for up to two weeks after dose adjustments.
Phenacetin
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Phenylbutazone
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Piroxicam
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.
Ramipril
Adverse Effect: postural hypotension (first dose)
Clinical Management: Start with a very low dose of the angiotensin converting enzyme (ACE) inhibitor in the evening and closely monitor blood pressure for a severe hypotensive response for four hours after the initial dose. Monitor for hypotension, fluid status, and body weight regularly for up to two weeks after dose adjustments.
Tenoxicam
Adverse Effect: Decreased diuretic and antihypertensive efficacy
Clinical Management: When administering thiazide diuretics and nonsteroidal antiinflammatory agents (NSAIDs) concurrently, monitor blood pressure and weight. Also, follow the patient for decreases in urine output and increased edema.

Ibuprofen

Imipenem and Cilastatin

ImipramineHydrochloride

ImmuneGlobulin

Indomethacin

Insulin (Regular)

InsulinGlargine (rDNA) inj