Anticholinergics: Additive anti-cholinergic effects. Avoid concomitant use. Barbiturates, opioids, tranquilizers
other CNS de-pressants: May add to or potentiate effects of these drugs. Reduce dosage of these drugs by 50%.
Epinephrine: May block epinephrines vasopressor action. It a vasoconstrictor is needed, use norepinephrine or phenylephrine. |