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| Interactions: | DydrogesteroneEnhance the clearance of progesterone and the progestogens
PhenobarbitoneAdverse Effect: Decreased effectiveness of griseofulvinClinical Management: Griseofulvin efficacy should be monitored. Dose of griseofulvin need to be increased, or phenobarbital might be administered in a divided dose three times daily to allow more opportunity for griseofulvin to be absorbed.
WarfarinAdverse Effect: decreased anticoagulant effectivenessClinical Management: In patients receiving oral anticoagulant therapy with warfarin, the prothrombin time ratio or international normalized ratio (INR) should be closely monitored with the addition and withdrawal of treatment with griseofulvin, and should be reassessed periodically during concurrent therapy. |
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