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| Interactions: | Acetazolamide: May increase serum ephedrine levels. Avoid concomitant use.
Alpha blockers, guanethidine: May decrease vasopressor effects of ephedrine. Monitor child closely.
Antihypertensives: May decrease effects. Moni-tor blood pressure.
Atropine: Blocked reflex bradycardia and en-hanced pressor effects. Monitor child closely.
Beta-blockers: May block CV and bronchodilat-ing effects of ephedrine. Monitor child.
Cardiac glycosides, general anesthetics (espe-cially cyclopropane, halothane): May sensitize myocardium to effects of ephedrine, causing ar-rhythmias. Monitor child closely.
Diuretics, methyldopa, reserpine: May decrease ephedrines pressor effects. Monitor child.
Ergot alkaloids: May enhance vasoconstrictor ac-tivity. Avoid concomitant use.
Levodopa: May enhance risk of ventricular ar-rhythmias. Monitor child closely.
MAO inhibitors, tricyclic antidepressants: May potentiate pressor effects of ephedrine, possibly resulting in hypertensive crisis. Allow 14 days to lapse after withdrawal of MAO inhibitor before us-ing ephedrine.
Sympathomimetics: May add to their effects and toxicity. Avoid concomitant use.
Theophylline derivatives: Co-administration re-portedly causes more adverse reactions than with either drug used alone. Avoid concomitant use. |
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