Bacteremia; septicemia; UTI; respiratory, bone, joint, gyn, intra-abdominal, skin infection
Neonate < 1 wk: 50 mg/kg IV or IM qd.
Neonate 1-4 wk and = 2 kg: 50 mg/kg IV or IM qd.
Neonate 1-4 wk and > 2 kg: 50-75 mg/kg IV or IM qd.
Infant, child: 50-75 mg/kg IV or IM qd divided in doses q 12 h.
Adolescent, adult: 1-2 gram IM or IV qd or in divided doses bid. Max 4 gram/day.
Meningitis, endocarditis
Neonate, infant, and child: 80-100 mg/kg IV or IM qd or divided q 12 h × 7-21 day for meningitis and 28 day for endocarditis; max 4 gram/day.
Adolescent, adult: 1-2 gram IV or IM q 12 h × 10-14 day for meningitis and 3-4 wk for endocarditis.
Perioperative prophylaxis
Adult: 1 gram IM or IV 30 min-2 h before surgery.
Uncomplicated gonorrhea
Child < 45 kg: 125 mg IM in 1 dose.
Child = 45 kg, adolescent, adult: 125-250 mg IM in 1 dose; 1-2 gram IM or IV qd until improvement.
Sexually transmitted epididymitis, PID
Adolescent, adult: 250 mg IM in 1 dose; follow up with other antibiotics.
Anti-infective after sexual assault
Adolescent, adult: 125 mg IM in 1 dose with other antibiotics.
Lyme disease
Child: 75-100 mg/kg IM or IV qd × 14-30 day.
Adult: 2 gram IM or IV qd × 14-30 day.
OM
Child: 50 mg/kg IM (max 1 gram) in 1 dose. |