Acenocoumarol
Adverse Effect: decreased Acenocoumarol effectiveness Clinical Management: In patients receiving Acenocoumarol , the prothrombin time ratio or international normalized ratio (INR) should be closely monitored with the addition and withdrawal of treatment with Carbimazole , and should be reassessed periodically during concurrent therapy.
Digoxin
Adverse Effect: decreased digoxin efficacy Clinical Management: Monitor digoxin levels when carbimazole is concomitantly administered.
Phenindione
Adverse Effect: decreased Phenindione effectiveness Clinical Management: In patients receiving Phenindione , the prothrombin time ratio or international normalized ratio (INR) should be closely monitored with the addition and withdrawal of treatment with Carbimazole , and should be reassessed periodically during concurrent therapy.
Warfarin
Adverse Effect: decreased anticoagulant effectiveness Clinical Management: In patients receiving Warfarin , the prothrombin time ratio or international normalized ratio (INR) should be closely monitored with the addition and withdrawal of treatment with Carbimazole , and should be reassessed periodically during concurrent therapy. |