IV: Reduction of Cumulative Renal Toxicity with Chemotherapy: 910 mg/m2, administered for 15 minutes once daily, 30 minutes prior to chemotherapy.
IV: Reduction of Moderate to Severe Xerostomia from Radiation of the Head & Neck: 200 mg/m2 once daily as a 3-minute Infusion, 15-30 minutes prior to standard fraction radiation therapy (1.8-2.0 Gy). |