Ethinyloestradiol
Adverse Effect: Decrease in the plasma concentration of Ethinyl estradiol and can results in decreasing its contraceptive efficacy # Clinical Management: Additional caution regarding contraception should be exercised when contraceptive preparations containing Ethinyl estradiol and Pioglitazone are administered together.
Ketoconazole
Adverse Effect: Ketoconazole inhibit the metabolism of Pioglitazone considerably # Clinical Management: Monitor the glycemic control and adjust the dose accordingly |