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| Interactions: | ClomipramineAdverse Effect: hypertension, cardiac arrhythmias, and tachycardiaClinical Management: The vasoconstriction and other alpha-adrenergic effects of Isoprenaline are substantially enhanced in the presence of Clomipramine .Concomitant use should be avoided.
DothiepinAdverse Effect: hypertension, cardiac arrhythmias, and tachycardiaClinical Management: The vasoconstriction and other alpha-adrenergic effects of Isoprenaline are substantially enhanced in the presence of Dothiepin.Concomitant use should be avoided.
DoxepinAdverse Effect: hypertension, cardiac arrhythmias, and tachycardiaClinical Management: The vasoconstriction and other alpha-adrenergic effects of Isoprenaline are substantially enhanced in the presence of Doxepin. Concomitant use should be avoided.
ImipramineAdverse Effect: hypertension, cardiac arrhythmias, and tachycardiaClinical Management: The vasoconstriction and other alpha-adrenergic effects of Isoprenaline are substantially enhanced in the presence of Imipramine.Concomitant use should be avoided.
NortriptylineAdverse Effect: hypertension, cardiac arrhythmias, and tachycardiaClinical Management: The vasoconstriction and other alpha-adrenergic effects of Isoprenaline are substantially enhanced in the presence of Nortriptyline .Concomitant use should be avoided. If these drugs are given together, careful monitoring and a dose reduction of the sympathomimetic is required.
SelegilineAdverse Effect: Increased hypertensive effectsClinical Management: Monitor patients for clinical effects of acute blood pressure elevation (headache, arrhythmia, vomiting, fever). Should a hypertensive crisis develop, discontinue the drug and immediately begin medical therapy to lower blood pressure. Nitroprusside, nitroglycerin, phentolamine, and labetalol are among the drugs that have been successfully used.
TheophyllineAdverse Effect: Decreased theophylline concentrationsClinical Management: Theophylline serum concentrations should be closely monitored when isoproterenol is added, discontinued, or when dosing changes occur. Dosing adjustments of theophylline may be necessary.
TrimipramineAdverse Effect: hypertension, cardiac arrhythmias, and tachycardiaClinical Management: The vasoconstriction and other alpha-adrenergic effects of Isoprenaline are substantially enhanced in the presence of Trimipramine.Concomitant use should be avoided. |
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