|  | | Interactions: |  | AcenocoumarolAdverse Effect: Decreased anticoagulant effectivenessClinical Management: In patients receiving Acenocoumarol, the prothrombin time ratio or international normalized ratio (INR) should be closely monitored with the addition and withdrawal of treatment with Iodine , and should be reassessed periodically during concurrent therapy. Increased Acenocoumarol dose may be required to maintain the desired level of anticoagulation.WarfarinAdverse Effect: Decreased anticoagulant effectivenessClinical Management: In patients receiving Warfarin , the prothrombin time ratio or international normalized ratio (INR) should be closely monitored with the addition and withdrawal of treatment with Iodine , and should be reassessed periodically during concurrent therapy. Increased Warfarin dose may be required to maintain the desired level of anticoagulation. | 
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