Cimetidine: May reduce fluconazoles serum levels. Monitor child for desired effects.
Cyclosporine: May increase cyclosporine levels. Monitor cyclosporine levels.
Hydrochlorothiazide: Decreased clearance of flu-conazole, raising drug serum levels. Monitor child for side effects.
Isoniazid, phenytoin, rihampin, sulfonylureas, val-proic acid: Elevated hepatic transaminase levels. Monitor liver function.
Phenytoin: May significantly increase serum pheny-toin levels. Monitor serum phenytoin levels.
Rifampin: Lowered fluconazole levels. Monitor child for desired effects.
Sulfonylureas (such as glipizide, glyburide, tolbu-tamide): Increased hypoglycemic effects. Moni-tor glucose levels.
Warfarin: Enhanced hypoprothrombinemic ef-fects. Monitor INR.
Zidovudine: May increase activity of zidovudine. Monitor child closely. |