Infection
Child > 8 yr and = 45 kg: 4.4 mg/kg PO or IV qd divided q 12 h on day 1, then 2.2-4.4 mg/kg PO or IV qd as single or divided dose.
Child > 8 yr and > 45 kg, adult: 100 mg PO q 12 h on day 1, then 100 mg PO qd; or 200 mg IV on day 1 in 1 or 2 infusion, then 100-200 mg IV qd. Give IV infusion slowly (minimum 1 h). Infusion must be complete within 12 h (within 6 h in lactated Ringers solution or D5W in lactated Ringers solution).
Chlamydia; nongonococcal urethritis; uncomplicated urethral, endocervical, rectal infection
Adolescent, adult: 100 mg PO bid at least 7 day.
PID
Adolescent, adult: 250 mg IM ceftriaxone, then 100 mg doxycycline PO bid 10-14 day.
Prophylaxis for rape victims
Adolescent, adult: 100 mg PO bid × 7 day after single 2-gram PO dose of metronidazole with single 125-mg IM dose of ceftriaxone.
Lyme disease
Child = 8 yr, adult: 100 mg PO bid or tid × 10-30 day. |