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| Dosages: | Prevention of nausea, vomiting with chemotherapy-
(PO) Child 4-12 yr: 4 mg PO 30 min before chemotherapy, then 4 mg PO 4 and 8 h after 1st dose, then 4 mg q 8 h × 1-2 day after chemotherapy.
Child > 12 yr, adult: 8 mg PO 30 min before chemotherapy, then 8 mg PO 8 h after 1st dose, then 8 mg q 12 h × 1-2 day after chemotherapy.
(IV) Child > 4 yr, adult: 0.15 mg/kg IV over 15 min 30 min before chemotherapy, then 0.15 mg/kg IV 4 and 8 h after 1st dose. Or 32 mg IV over 15 min in 1 dose 30 min before chemotherapy.
Prevention of nausea, vomiting with radiation-
Adult: 8 mg PO tid.
Prevention of postoperative nausea, vomiting-
Child 2-12 yr and = 40 kg: 0.1 mg/kg IV over 2-5 min immed before anesthesia or shortly postoperative.
Child 2-12 yr and > 40 kg: 4 mg IV over 2-5 min immed before anesthesia or shortly postoperative.
Adult: 16 mg PO 1 h before anesthesia or 4 mg IV immed before anesthesia or shortly postoperative. |
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