Ventricular arrhythmias from MI, cardiac manipulation, cardiac glycosides Child: 0.5-1 mg/kg IV bolus, then infusion 20-50 mcg/min.
Adult: 50-100 mg (1-1.5 mg/kg) IV bolus at 25-50 mg/mi. Repeat q 3-5 min prn as tolerated. Max 300-mg total bolus over 1 h. At same time, begin infusion of 1-4 mg/min. If initial bolus given, give smaller bolus (usually ½ initial bolus) 5-10 min after start of infusion to maintenance therapeutic serum level. After 24 h of infusion, dec rate to 1-2 mg/min. Or 300 mg (4.3 mg/kg) IM in deltoid muscle in early stage of acute MI. Adjust dose in pts < 50 kg and in those with HF.
Status epilepticus Adult: 1 mg/kg IV bolus; then 0.5 mg/kg 2 min after 1st dose prn; or infusion 30 mcg/kg/min.
Local anesthesia of skin, mucous membranes, pain from dental extraction, stomatitis Child, adult: 2-5% solution, oint or 15 ml Xylocaine Viscous q 3-4 h to oral, nasal mucosa. |