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| Interactions: | Propranolol Adverse Effect Increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent Lacidipine and Acenocoumarol should be monitored for excessive bleeding, especially from the gastrointestinal tract.
AmiodaroneAdverse Effect Atrioventricular block and slowing of sinus rate Clinical Management Concurrent use of amiodarone and Lacidipine should be avoided in patients with sick sinus syndrome or partial AV (atrioventricular) block.
Atenolol Adverse Effect Hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Betaxolol Adverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Bisoprolol Adverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Carvedilol Adverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Celecoxib Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Celiprolol Adverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Esmolol Adverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Flurbiprofen Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Ibuprofen Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Ibuprofen Comb. Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Indomethacin Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Ketoconazole Adverse Effect increased Lacidipine serum concentrations and toxicity (dizziness, hypotension, flushing, headache, peripheral edema) Clinical Management Observe for development of toxicity associated with the Lacidipine (peripheral edema, dizziness, hypotension, flushing, headache). Consider reducing the dose of the Lacidipine or withdrawing one of the agents.
Ketoprofen Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Ketorolac Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
LabetalolAdverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
LevobunololAdverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Mefenamic AcidAdverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Meloxicam Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
MetoprololAdverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
NabumetoneAdverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Naproxen Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
NimesulideAdverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
OxprenololAdverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Oxyphenbutazone Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
ParacetamolAdverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Paracetamol Comb Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
PhenacetinAdverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Phenindione Adverse Effect an increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent Lacidipine and Phenindione should be monitored for excessive bleeding, especially from the gastrointestinal tract.
PhenylbutazoneAdverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Pindolol Adverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Piroxicam Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
Propranolol Adverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Rifampicin Adverse Effect Decreased lacidipine efficacy
Tenoxicam Adverse Effect An increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent NSAID and calcium channel blocker therapy should be monitored for signs of gastrointestinal hemorrhage, such as weakness, nausea, and blood in the stool.
TimololAdverse Effect hypotension and/or bradycardia Clinical Management If concurrent therapy is required, monitor cardiac function carefully, particularly in patients predisposed to heart failure.
Warfarin Adverse Effect an increased risk of gastrointestinal hemorrhage Clinical Management Patients who are receiving concurrent Lacidipine and Warfarin should be monitored for excessive bleeding, especially from the gastrointestinal tract. |
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