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Dosages: | CMV retinitis in AIDS Adolescent, adult: 60 mg/kg IV as induction treatment in pts with normal renal function. Give as IV infusion over 1 h q 8 h × 2-3 wk. Or 90 mg/kg IV over 1½ -2 h 12 h × 2-3 wk. Follow with maintenance infusion of 90 mg/kg qd over 2 h; increase prn as tol to 120 mg/kg qd if disease progresses.
Mucocutaneous acyclovir-resistant HSV infection Adult: 40 mg/kg IV infusion over 1 h q 8-12 h × 2-3 wk.
Varicella zoster infection Adult: 40 mg/kg IV q 8 h × 10-21 day or until healing is complete. |
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