Antacids Comb.
Adverse Effect: decreased penicillamine effectiveness Clinical Management: Concurrent administration of penicillamine and antacids is not recommended. If concurrent use cannot be avoided, penicillamine should be taken on an empty stomach, at least one hour before or two hours after taking antacids.
Auranofin ( Gold )
Adverse Effect: Increased bone marrow depression, rash Clinical Management: Monitor for bone marrow toxicity and discontinue gold therapy if necessary.
Digoxin
Adverse Effect: decreased digoxin effectiveness Clinical Management: Monitor clinical signs of decreased digoxin effectiveness, adjust the dose as needed. |