INTATHECAL: Rx. & Px. OF MENINGEAL LEUKAEMIA:Dose ranges from 5-75mg/m2 surface area. Most commonly used dosage is 30mg/m2 every 4 days until CSF is normal followed by 1 additional course.
IV: OTHER INDICATIONS:Given in combination with other drugs.100mg/m2/day by continous Infsn. for 7 days OR 100mg/m2/day by IV every 12 hours for 7 days. |