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Interactions: | Carbamazepine Adverse Effect Reduced efficacy of Levonorgestrel due to the increased metabolism of the drug by induction of hepatic microsomal enzymes by Carbamazepine Clinical Management: Women receiving concomitant administration should be warned of reduced efficacy and those receiving long-term therapy with hepatic enzyme inducers, another method of contraception should be considered.
Phenytoin Adverse Effect Reduced efficacy of Levonorgestrel due to the increased metabolism of the drug by induction of hepatic microsomal enzymes by Phenytoin Clinical Management: Women receiving concomitant administration should be warned of reduced efficacy and those receiving long-term therapy with hepatic enzyme inducers, another method of contraception should be considered.
Rifampicin Adverse Effect Reduced efficacy of Levonorgestrel due to the increased metabolism of the drug by induction of hepatic microsomal enzymes by Rifampicin Clinical Management: Women receiving concomitant administration should be warned of reduced efficacy and those receiving long-term therapy with hepatic enzyme inducers, another method of contraception should be considered. |
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