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| Interactions: | Acarbose Adverse Effect: increased risk of hypoglycemia
Clinical Management: Monitor closely blood glucose concentrations when acarbose is added to or withdrawn from therapy. Doses of either or both acarbose and insulin may need to be adjusted to minimize hypoglycemic effects. Patients receiving these medications should be counselled to carry a supply of glucose tablets.
AspirinAdverse Effect: Hypoglycemia (CNS depression, seizures)
Clinical Management: Monitor the patients blood glucose and the patient for clinical signs of hypoglycemia. Switch from aspirin to acetaminophen if clinically relevant and/or appropriate.
Atenolol Adverse Effect: hypoglycemia, hyperglycemia, or hypertension
Clinical Management: If the use of a beta blocker is required in a diabetic, watch for decreased diabetic control by monitoring the patients glucose carefully. Cardioselective beta blockers (atenolol, metoprolol) cause less disturbance of glucose metabolism and less masking of hypoglycemic effects. Propranolol accounts for the majority of positive reports of an interaction and should clearly be avoided.
BisoprololAdverse Effect: hypoglycemia, hyperglycemia, or hypertension
Clinical Management: If the use of a beta blocker is required in a diabetic, watch for decreased diabetic control by monitoring the patients glucose carefully. Cardioselective beta blockers (atenolol, metoprolol) cause less disturbance of glucose metabolism and less masking of hypoglycemic effects. Propranolol accounts for the majority of positive reports of an interaction and should clearly be avoided.
CeliprololAdverse Effect: hypoglycemia, hyperglycemia, or hypertension
Clinical Management: If the use of a beta blocker is required in a diabetic, watch for decreased diabetic control by monitoring the patients glucose carefully. Cardioselective beta blockers (atenolol, metoprolol) cause less disturbance of glucose metabolism and less masking of hypoglycemic effects. Propranolol accounts for the majority of positive reports of an interaction and should clearly be avoided.
MetoprololAdverse Effect: hypoglycemia, hyperglycemia, or hypertension
Clinical Management: If the use of a beta blocker is required in a diabetic, watch for decreased diabetic control by monitoring the patients glucose carefully. Cardioselective beta blockers (atenolol, metoprolol) cause less disturbance of glucose metabolism and less masking of hypoglycemic effects. Propranolol accounts for the majority of positive reports of an interaction and should clearly be avoided.
Oxprenolol Adverse Effect: hypoglycemia, hyperglycemia, or hypertension
Clinical Management: If the use of a beta blocker is required in a diabetic, watch for decreased diabetic control by monitoring the patients glucose carefully. Cardioselective beta blockers (atenolol, metoprolol) cause less disturbance of glucose metabolism and less masking of hypoglycemic effects. Propranolol accounts for the majority of positive reports of an interaction and should clearly be avoided.
PindololAdverse Effect: hypoglycemia, hyperglycemia, or hypertension
Clinical Management: If the use of a beta blocker is required in a diabetic, watch for decreased diabetic control by monitoring the patients glucose carefully. Cardioselective beta blockers (atenolol, metoprolol) cause less disturbance of glucose metabolism and less masking of hypoglycemic effects. Propranolol accounts for the majority of positive reports of an interaction and should clearly be avoided.
Propranolol Adverse Effect: hypoglycemia, hyperglycemia, or hypertension
Clinical Management: If the use of a beta blocker is required in a diabetic, watch for decreased diabetic control by monitoring the patients glucose carefully. Cardioselective beta blockers (atenolol, metoprolol) cause less disturbance of glucose metabolism and less masking of hypoglycemic effects. Propranolol accounts for the majority of positive reports of an interaction and should clearly be avoided.
Selegiline Adverse Effect: excessive hypoglycemia, CNS depression, and seizures
Clinical Management: Blood glucose levels should be closely monitored when Selegiline is added or discontinued in a patient receiving Insulin Lispro . Lower dose of Insulin Lispro may be required with concomitant therapy.
Tolbutamide Adverse Effect: hypoglycemia (CNS depression, seizures) Clinical Management: Monitor blood glucose more aggressively during concurrent use. |
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