Lower respiratory, skin and skin-structure, gyn infection Adult = 70 kg: 500-750 mg IM q 12 h.
Intra-abdominal infection Adult = 70 kg: 750 mg IM q 12 h. In pts weighing < 70 kg, dosages vary.
Serious respiratory infection, UTI; intra-abdominal, gyn, bone, joint or skin infection; bacterial septicemia; endocarditis Neonate < 1 wk and = 1.5 kg: 25 mg/kg IV q 12 h.
Neonate 1-4 wk and = 1.5 kg: 25 mg/kg IV q 8 h.
Infant 4 wk-3 month and = 1.5 kg: 25 mg/kg IV q 6 h.
Infant, child = 3 month: 15-25 mg/kg IV q 6 h. Max in ped pts 2-4 gram qd. Doses as high as 90 mg/kg qd have been used in older child with CF.
Adult = 70 kg: 250 mg-1 gram IV infusion q 6-8 h. Max 50 mg/kg/day or 4 gram/day, whichever is less. In pts weighing < 70 kg dosages vary. |