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| Interactions: | Frusemide
Adverse Effect: an increased risk of cephaloridine toxicity Clinical Management: Monitor renal function in patients with pre-existing renal disease who are receiving concurrent furosemide and cephaloridine. Even in the presence of normal renal function, it has been suggested that the dose of cephaloridine should not exceed 4 grams daily.
Gentamicin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Gentamicin with Cephaloridine could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Neomycin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Neomycin with Cephaloridine could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Netilmicin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Netilmicin with Cephaloridine could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Probenecid
Adverse Effect: cephalosporin toxicity (neuromuscular toxicity, CNS toxicity) Clinical Management: If clinical symptoms of cephalosporin toxicity occur, reduce the dose of Cephaloridine .
Sisomicin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Sisomicin with Cephaloridine could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Streptomycin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Streptomycin with Cephaloridine could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Tobramycin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Tobramycin with Cephaloridine could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity. |
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