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| Interactions: | Gentamicin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Gentamicin with Ceftizoxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Neomycin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Neomycin with Ceftizoxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Netilmicin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Netilmicin with Ceftizoxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Probenecid
Adverse Effect: cephalosporin toxicity (neuromuscular toxicity, CNS toxicity) Clinical Management: If clinical symptoms of cephalosporin toxicity occur, reduce the dose of Ceftizoxime.
Sisomicin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Sisomicin with Ceftizoxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Streptomycin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Streptomycin with Ceftizoxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity.
Tobramycin
Adverse Effect: an increased risk of nephrotoxicity Clinical Management: Coadministration of Tobramycin with Ceftizoxime could produce additive nephrotoxic effects. Use of these agents should be avoided in patients with prior renal insufficiency. If coadministration of these two antibiotic classes is necessary, patients should be monitored for evidence of nephrotoxicity. |
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