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Interactions: | Carbamazepine
Adverse Effect: decreased ethosuximide serum concentrations Clinical Management: careful evaluation of clinical response and serum drug level monitoring is necessary.
Phenobarbitone
Adverse Effect: decreased ethosuximide serum concentrations Clinical Management: Patients should be closely monitored for increased seizure activity, and serum concentrations of ethosuximide should be carefully followed. An increase in the ethosuximide dose may be needed.
Phenytoin
Adverse Effect: decreased ethosuximide serum concentrations Clinical Management:If these two agents are used together, careful evaluation of clinical response and serum drug level monitoring is necessary.
Sodium Valproate
Adverse Effect: An increased risk of ethosuximide toxicity |
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