Hypersensitivity to Penicillins and other Beta-Lactam Antibiotics, Pseudomembranous Colitis (in patients developing Diarrhoea while being treated with the drug), Liver Cirrhosis, Severe Renal impairment (creatinine clearance 30ml/minute, the dosing interval to be prolonged to 24 hours), Patients on Haemodialysis (dose frequency to be adjusted to 3 times a week after haemodialysis). |