Fungal infection, endocarditis; septicemia
Child, adult: Test dose of 1 mg in 20 ml D5W IV over 20-30 min. If tol, 0.25-0.30 mg/kg/day IV. Increase by 5-10 mg/day untill dose is 1mg/kg/day or 1.5 mg/kg every other day.
Sporotrichosis
Adult: 0.4-0.5 mg/kg/day IV × 2-3 month. Max 2.5 gram over 9 month.
Aspergillosis
Adult: 0.5-0.6 mg/kg/day IV. Max 1.5 mg/kg/day. Total IV dose 1.5-4 gram over 11 month. |