Congenitalsyphilis- Asymptomatic neonate with normal CSF whose mother maynot have received treatment during pregnancy: 50,000 U/kg IM in 1 dose. Child < 2 yr: 50,000 U/kg IM in 1 dose.
Untreated congenital syphilis- Child > 1 yr: 50,000 U/kg IM q wk × 3 wk after 10-14 day of penicillin G potassium or sodium treatment.
Group A streptococci upper respiratory tract infection- Child < 27 kg: 300,000-600,000 U IM in 1 dose. Child = 27 kg: 900,000 U IM in 1 dose. Adult: 1.2 million U IM in 1 dose.
Group A streptococci pharyngitis, prevention of rheumatic fever- Child = 27 kg: 600,000 U IM in 1 dose. Child > 27 kg, adult: 1.2 million U IM in 1 dose.
Primary, secondary syphilis- Infant, child = 1 month: 50,000 U/kg IM in 1 dose. Max 2.4 million U. Adolescent, adult: 2.4 million U IM in 1 dose. |